BDBM772434 US12419873, Compound 9-5

SMILES N#CCC(=O)N1CC2(CCC(c3cccc4nc(NC(=O)[C@@H]5CC5(F)F)nn34)CC2)C1

InChI Key InChIKey=KMLAKPXUCUWAFX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 772434   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Zhuhai United Laboratories Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 772434BDBM772434(US12419873, Compound 9-5)
Affinity DataIC50: 175nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Zhuhai United Laboratories Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 772434BDBM772434(US12419873, Compound 9-5)
Affinity DataIC50: 224nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Zhuhai United Laboratories Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 772434BDBM772434(US12419873, Compound 9-5)
Affinity DataIC50: 624nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Zhuhai United Laboratories Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 772434BDBM772434(US12419873, Compound 9-5)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent