BDBM772734 (E)-N-(2-((1R,5S,6s)-3- (2-(diethylamino)-2-oxo- 1-phenylethyl)-3- azabicyclo[3.1.0]hexan-6- yl)ethyl)-3-(pyridin-3- yl)acrylamide::US12421210, Example 318

SMILES CCN(CC)C(=O)C(c1ccccc1)N1C[C@@H]2[C@@H](CCNC(=O)/C=C/c3cccnc3)[C@@H]2C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772734   

TargetNicotinamide phosphoribosyltransferase(Human)
New York University

US Patent
LigandPNGBDBM772734((E)-N-(2-((1R,5S,6s)-3- (2-(diethylamino)-2-oxo- 1...)
Affinity DataIC50: 100nMAssay Description:To test the inhibition activity (IC50) of the compounds of the disclosure against the enzymatic activity of NAMPT, the compounds were dissolved in 10...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/6/2026
Entry Details
US Patent