BDBM773894 US12427146, Compound 129

SMILES COc1ccn2c(-c3ccnc(NC4CC4)n3)c(-c3cccc(NS(=O)(=O)c4c(F)ccc(C)c4F)c3F)nc2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 773894   

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773894(US12427146, Compound 129)
Affinity DataIC50: 7.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773894(US12427146, Compound 129)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent