BDBM773919 US12427146, Compound 154

SMILES CNc1nccc(-c2sc(-c3cncc(F)c3)nc2-c2cc(C)cc(NS(=O)(=O)c3c(F)cccc3F)c2F)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 773919   

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773919(US12427146, Compound 154)
Affinity DataIC50: 12.5nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773919(US12427146, Compound 154)
Affinity DataIC50: 550nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent