BDBM773928 US12427146, Compound 163

SMILES O=S(=O)(Nc1cccc(-c2nc(N3CCCCC3)sc2-c2ccnc(NC3CC3)n2)c1F)c1c(F)cccc1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 773928   

TargetTyrosine-protein kinase CSK(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773928(US12427146, Compound 163)
Affinity DataIC50: 7.40nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lck(Human)
Inventisbio Co.

US Patent
LigandPNGBDBM773928(US12427146, Compound 163)
Affinity DataIC50: 550nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent