BDBM774096 2,2-Difluoro-3-((5S,7R)-5-(5-(((S)-1-(3-fluoropropyl)pyrrolidin-3-yl)amino)pyridin-2-yl)-7-methyl-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6(5H)-yl)propan-1-ol 4::US12428428, Example 4

SMILES C[C@@H]1Cc2cc3c(cc2[C@@H](c2ccc(N[C@H]4CCN(CCCF)C4)cn2)N1CC(F)(F)CO)OCO3

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 774096   

TargetEstrogen receptor(Human)
Jiangsu Hengrui Medicine Co.

US Patent
LigandPNGBDBM774096(2,2-Difluoro-3-((5S,7R)-5-(5-(((S)-1-(3-fluoroprop...)
Affinity DataIC50: 0.370nMAssay Description:An ERE was cloned upstream of the luciferase gene, and MCF-7/ERE-luciferase monoclonal cells were selected by transfection of MCF-7 (TCHu74, National...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent