BDBM774116 US12428433, Example 3

SMILES C[C@H]1Nc2nc3c(cnn3cc2F)C(=O)N[C@H]2C[C@H](C2)Oc2ncc(F)cc21

InChI Key InChIKey=JXLZJPYLDDSEQF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 774116   

TargetHigh affinity nerve growth factor receptor(Human)
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774116BDBM774116(US12428433, Example 3)
Affinity DataIC50: 0.360nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774116BDBM774116(US12428433, Example 3)
Affinity DataIC50: 0.890nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Scinnohub Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774116BDBM774116(US12428433, Example 3)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/14/2026
Entry Details
US Patent