BDBM774725 7-((2-(4-aminopiperidin-1-yl)-6-(4-cyano-3-fluorophenyl)pyridin-4-yl)oxy)-N-hydroxyheptanamide hydrochloride::US20250304549, Example 31

SMILES N#Cc3ccc(c2cc(OCCCCCCC(=O)NO)cc(N1CCC(N)CC1)n2)cc3F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774725   

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774725(7-((2-(4-aminopiperidin-1-yl)-6-(4-cyano-3-fluorop...)
Affinity DataIC50: 0.25nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774725(7-((2-(4-aminopiperidin-1-yl)-6-(4-cyano-3-fluorop...)
Affinity DataIC50: 1.78nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774725(7-((2-(4-aminopiperidin-1-yl)-6-(4-cyano-3-fluorop...)
Affinity DataIC50: 263nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774725(7-((2-(4-aminopiperidin-1-yl)-6-(4-cyano-3-fluorop...)
Affinity DataIC50: 311nMAssay Description:The effect of the compounds on LSD1 enzyme activity was examined using the HTRF technique to assess the level of inhibition. Initially, a master solu...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent