BDBM774790 (E)-3-(4-((1-(3- Cyano-4-(4- cyanophenyl)-5- (3-hydroxy-4- methoxyphenyl) pyridin-2- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 118

SMILES COc5ccc(c3cnc(N2CCC(NCc1ccc(/C=C/C(=O)NO)cc1)CC2)c(C#N)c3c4ccc(C#N)cc4)cc5O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 774790   

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774790BDBM774790((E)-3-(4-((1-(3- Cyano-4-(4- cyanophenyl)-5- (3-hy...)
Affinity DataIC50: 0.440nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774790BDBM774790((E)-3-(4-((1-(3- Cyano-4-(4- cyanophenyl)-5- (3-hy...)
Affinity DataIC50: 0.580nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774790BDBM774790((E)-3-(4-((1-(3- Cyano-4-(4- cyanophenyl)-5- (3-hy...)
Affinity DataIC50: 0.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774790BDBM774790((E)-3-(4-((1-(3- Cyano-4-(4- cyanophenyl)-5- (3-hy...)
Affinity DataIC50: 30.3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent