BDBM774888 3-(3-chloro-4-((1-(3- cyano-4-(4-cyano-3- fluorophenyl)-5-(3- hydroxy-4- methoxyphenyl) pyridin- 2-yl)piperidin-4- yl)amino)methyl) phenyl)- N- hydroxypropanamide formate::US20250304549, Example 222

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(CCC(=O)NO)cc4Cl)CC3)c(C#N)c2-c2ccc(C#N)c(F)c2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 774888   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774888(3-(3-chloro-4-((1-(3- cyano-4-(4-cyano-3- fluoroph...)
Affinity DataIC50: 0.0300nMAssay Description:The effect of the compounds on LSD1 enzyme activity was examined using the HTRF technique to assess the level of inhibition. Initially, a master solu...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774888(3-(3-chloro-4-((1-(3- cyano-4-(4-cyano-3- fluoroph...)
Affinity DataIC50: 11.5nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent