BDBM774891 (E)-3-(5- (((1-(3-Cyano- 4-(4-cyano-3- fluorophenyl)-5-(1-(2- hydroxy-2- methylpropyl)-1H- benzo[d][1,2,3]triazol- 5-yl)pyridin-2- yl)piperidin-4- yl)amino)methyl) pyridin- 2-)-N- hydroxyacrylamide formate::US20250304549, Example 225

SMILES CC(C)(O)Cn1nnc2cc(-c3cnc(N4CCC(NCc5ccc(/C=C/C(=O)NO)nc5)CC4)c(C#N)c3-c3ccc(C#N)c(F)c3)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 774891   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774891((E)-3-(5- (((1-(3-Cyano- 4-(4-cyano-3- fluoropheny...)
Affinity DataIC50: 0.350nMAssay Description:The effect of the compounds on LSD1 enzyme activity was examined using the HTRF technique to assess the level of inhibition. Initially, a master solu...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774891((E)-3-(5- (((1-(3-Cyano- 4-(4-cyano-3- fluoropheny...)
Affinity DataIC50: 3.43nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent