BDBM774914 (E)-3-(4-(((1-(3''- Cyano-5''-(3- hydroxy-4- methoxyphenyl)- 6-nitro-[3,4''- bipyridin]-2''- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 248

SMILES COc1ccc(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c(C#N)c2-c2ccc([N+](=O)[O-])nc2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 774914   

TargetHistone deacetylase 1(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774914BDBM774914((E)-3-(4-(((1-(3'- Cyano-5'-(3- hydroxy-4- methoxy...)
Affinity DataIC50: 0.610nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774914BDBM774914((E)-3-(4-(((1-(3'- Cyano-5'-(3- hydroxy-4- methoxy...)
Affinity DataIC50: 0.620nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 774914BDBM774914((E)-3-(4-(((1-(3'- Cyano-5'-(3- hydroxy-4- methoxy...)
Affinity DataIC50: 0.810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent