BDBM774936 (E)-3-(4-(((1-(6-Cyano- 3''-fluoro-5''-(2-fluoro-5- hydroxy-4- methoxyphenyl)-[3,4''- bipyridin]-2''- yl)piperidin-4- yl)amino)methyl) phenyl)-N- hydroxyacrylamide formate::US20250304549, Example 270

SMILES COc1cc(F)c(-c2cnc(N3CCC(NCc4ccc(/C=C/C(=O)NO)cc4)CC3)c(F)c2-c2ccc(C#N)nc2)cc1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 774936   

TargetHistone deacetylase 1/8(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774936((E)-3-(4-(((1-(6-Cyano- 3'-fluoro-5'-(2-fluoro-5- ...)
Affinity DataIC50: 0.320nMAssay Description:The effect of the compound on the enzymatic activity of pan-HDAC and two isoforms (HDAC1 and HDAC8) was examined using the HDAC-Glo I/II Assay and Sc...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM774936((E)-3-(4-(((1-(6-Cyano- 3'-fluoro-5'-(2-fluoro-5- ...)
Affinity DataIC50: 24.8nMAssay Description:The effect of the compounds on LSD1 enzyme activity was examined using the HTRF technique to assess the level of inhibition. Initially, a master solu...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent