BDBM774956 4-[(4-{3-[(4-methyl-1,2,4-triazol-3-yl)methyl]oxetan-3-yl}-6-(6-{[(3S)-3-methylpiperidin-1-yl]methyl}-1-oxo-4-(trifluoromethyl)-3H-isoindol-2-yl)pyridin-2-yl)oxy]butanenitrile::US20250304563, Compound 122

SMILES C[C@H]1CCCN(Cc2cc3c(c(C(F)(F)F)c2)CN(c2cc(C4(Cc5nncn5C)COC4)cc(OCCCC#N)n2)C3=O)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 774956   

LigandPNGBDBM774956(4-[(4-{3-[(4-methyl-1,2,4-triazol-3-yl)methyl]oxet...)
Affinity DataIC50: 3nMAssay Description:Compounds were assessed for binding activity to Cbl-b by their ability to compete with and displace a probe comprised of BODIPY-FL fluorophore conjug...More data for this Ligand-Target Pair
Ligand Info
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Date in BDB:
1/19/2026
Entry Details
US Patent