BDBM775140 US12435062, Compound 53

SMILES COc1cc(Oc2ccnc(-c3cnn(C)c3)c2)ccc1NC(=O)c1cnc(C)n(C)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775140   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM775140(US12435062, Compound 53)
Affinity DataIC50: 0.135nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent