BDBM775223 1,2-dimethyl-N-(5-((2-(1-(methyl-d3)-1H-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)-6-oxo-1,6-dihydropyrimidine-5-carboxamide::US12435062, Compound 129

SMILES [2H]C([2H])([2H])n1cc(-c2cc(Oc3ccc(NC(=O)c4cnc(C)n(C)c4=O)nc3)ccn2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 775223   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM775223(1,2-dimethyl-N-(5-((2-(1-(methyl-d3)-1H-pyrazol-4-...)
Affinity DataIC50: 4nMAssay Description:1) Kinase reaction (10 μL system)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the corresponding volume of 8% DMSO...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/21/2026
Entry Details
US Patent