BDBM77545 MLS000708339::N-[4-(4-isobutyrylpiperazino)phenyl]-5-nitro-2-furamide::N-[4-[4-(2-methyl-1-oxopropyl)-1-piperazinyl]phenyl]-5-nitro-2-furancarboxamide::N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-5-nitro-furan-2-carboxamide::N-[4-[4-(2-methylpropanoyl)piperazin-1-yl]phenyl]-5-nitrofuran-2-carboxamide::SMR000287806::cid_1087128

SMILES C[C@]12CCC(CC(=O)O)CC1[C@H](O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

InChI Key InChIKey=GZRYTHJYFZWAQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77545   

TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77545BDBM77545(2-(6beta-hydroxy-17-oxoandrostane-3-yl)acetic acid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2026
Entry Details
US Patent