BDBM775561 US12435089, Example 4

SMILES [2H]C([2H])([2H])Oc1ccc(F)cc1[C@@H](C)Nc1ccn2ncc(C3=NOC(C)(C)N3)c2n1

InChI Key InChIKey=HYHRGQAQGDRQRW-GKOSEXJESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 775561   

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 27.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 27.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetALK tyrosine kinase receptor [G1202R](Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 775561BDBM775561(US12435089, Example 4)
Affinity DataIC50: 27.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent