BDBM775798 (S)-4''-fluoro-4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)pyrrolidin-1-yl)biphenyl-3-carboxamide ::US12435061, Compound 1-65

SMILES NC(=O)c1cc(-c2ccc(F)cc2)ccc1N1CC[C@H](Oc2ccc(C(F)(F)F)cn2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 775798   

LigandPNGBDBM775798((S)-4'-fluoro-4-(3-(5-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 417nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM775798((S)-4'-fluoro-4-(3-(5-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 1.14E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent