BDBM775943 (S)-(2''-ethyl-4-(3-(5-(trifluoromethyl)pyridin-2-yloxy)pyrrolidin-1-yl)biphenyl-3-yl)methanol ::US12435061, Compound 1-149

SMILES CCc1ccccc1-c1ccc(N2CC[C@H](Oc3ccc(C(F)(F)F)cn3)C2)c(CO)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 775943   

LigandPNGBDBM775943((S)-(2'-ethyl-4-(3-(5-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 10.7nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM775943((S)-(2'-ethyl-4-(3-(5-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 34.7nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent