BDBM776175 (5-fluoropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-isopropylphenoxy)phenyl)pyrrolidin-1-yl)methanone ::US12435061, Compound 2-16

SMILES CC(C)c1ccccc1Oc1ccc(C2CCN(C(=O)c3ccc(F)cn3)C2)c(CO)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776175   

LigandPNGBDBM776175((5-fluoropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-i...)
Affinity DataIC50: 25.7nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM776175((5-fluoropyridin-2-yl)(3-(2-(hydroxymethyl)-4-(2-i...)
Affinity DataIC50: 9.65E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent