BDBM776185 (5-fluoropyridin-2-yl)(3-(3-(hydroxymethyl)-2''-isopropylbiphenyl-4-yl)pyrrolidin-1-yl)methanone ::US12435061, Compound 2-29

SMILES CC(C)c1ccccc1-c1ccc(C2CCN(C(=O)c3ccc(F)cn3)C2)c(CO)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776185   

LigandPNGBDBM776185((5-fluoropyridin-2-yl)(3-(3-(hydroxymethyl)-2'-iso...)
Affinity DataIC50: 5.56nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM776185((5-fluoropyridin-2-yl)(3-(3-(hydroxymethyl)-2'-iso...)
Affinity DataIC50: 7.38E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent