BDBM776197 (3-(2''-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)pyrrolidin-1-yl)(5-fluoropyridin-2-yl)methanone ::US12435061, Compound 2-72

SMILES O=C(c1ccc(F)cn1)N1CCC(c2ccc(-c3ccccc3C3CC3)cc2CO)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776197   

LigandPNGBDBM776197((3-(2'-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)...)
Affinity DataIC50: 3.99nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

LigandPNGBDBM776197((3-(2'-cyclopropyl-3-(hydroxymethyl)biphenyl-4-yl)...)
Affinity DataIC50: 9.24E+3nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent