BDBM776219 US12435061, Compound KM-054-E1

SMILES CNc1cncc(C(=O)N2CC[C@H](c3ccc(-c4ccccc4C4CC4)cc3CO)C2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 776219   

LigandPNGBDBM776219(US12435061, Compound KM-054-E1)
Affinity DataIC50: 10nMAssay Description:TRPV3 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent