BDBM776348 [3-(4-chloro-3-fluoro-phenyl)pyrrolidin-1-yl]-(3-pyridazin-4-yl-1H-pyrazol-5-yl)methanone::WO2025045746, Example 39

SMILES ClC1=C(C=C(C=C1)C1CN(CC1)C(=O)C1=CC(=NN1)C1=CN=NC=C1)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 776348   

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776348([3-(4-chloro-3-fluoro-phenyl)pyrrolidin-1-yl]-(3-p...)
Affinity DataIC50: 73nMAssay Description:Enzymatic reactions were ran in a 10µL volume consisting of 8nM human SARM1 (aa28-724), 100µM Nicotinamide (NMN) and 30µM Nicotinamide Adenine Dincul...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025045746