BDBM776356 (4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[3-(3,4-difluorophenyl)pyrrolidin-1-yl]methanone::WO2025045746, Example 47

SMILES ClC=1C(=NNC1C(=O)N1CC(CC1)C1=CC(=C(C=C1)F)F)C1=CN=NC=C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 776356   

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776356((4-chloro-3-pyridazin-4-yl-1H-pyrazol-5-yl)-[3-(3,...)
Affinity DataIC50: 142nMAssay Description:Enzymatic reactions were ran in a 10µL volume consisting of 8nM human SARM1 (aa28-724), 100µM Nicotinamide (NMN) and 30µM Nicotinamide Adenine Dincul...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025045746