BDBM776372 [(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-fluoro-3-pyridazin-4-yl-1H-pyrazol-5-yl)methanone::WO2025045746, Example 63

SMILES ClC1=CC=C(C=C1)[C@@H]1CN(CC1)C(=O)C1=C(C(=NN1)C1=CN=NC=C1)F

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 776372   

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776372([(3R)-3-(4-chlorophenyl)pyrrolidin-1-yl]-(4-fluoro...)
Affinity DataIC50: 95nMAssay Description:Enzymatic reactions were ran in a 10µL volume consisting of 8nM human SARM1 (aa28-724), 100µM Nicotinamide (NMN) and 30µM Nicotinamide Adenine Dincul...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025045746