BDBM776382 (3R,4S)-4-(4-chlorophenyl)-1-(3-pyridazin-4-yl-1H-pyrazole-5-carbonyl)pyrrolidine-3-carbonitrile::WO2025045746, Example 73

SMILES ClC1=CC=C(C=C1)[C@@H]1[C@H](CN(C1)C(=O)C1=CC(=NN1)C1=CN=NC=C1)C#N

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 776382   

TargetNAD(+) hydrolase SARM1 [28-724](Human)
695 Avenue de la Résistance

WIPO
LigandPNGBDBM776382((3R,4S)-4-(4-chlorophenyl)-1-(3-pyridazin-4-yl-1H-...)
Affinity DataIC50: 30nMAssay Description:Enzymatic reactions were ran in a 10µL volume consisting of 8nM human SARM1 (aa28-724), 100µM Nicotinamide (NMN) and 30µM Nicotinamide Adenine Dincul...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/24/2026
Entry Details
WIPO WO2025045746