BDBM778517 (10aR,12aS)- or (10aS,12aR)-3- cyclopropyl-1-methyl-8- (trifluoromethyl)- 1,4,10,10a,11,12,12a,13-octahydro- 5,9-(azeno)cyclobuta[k]pyrazolo- [3,4-b][1]oxa[4,6,10]triazacyclo- tridecine::US20250313575, Ex-1.9

SMILES Cn1nc(C2CC2)c2c1OCC1CCC1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778517   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778517((10aR,12aS)- or (10aS,12aR)-3- cyclopropyl-1-methy...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent