BDBM778525 2-((10aR,12aR)-3-cyclopropyl-8- (trifluoromethyl)- 10,10a,11,12,12a,13-hexahydro-5,9- (azeno)cyclobuta[k]pyrazolo[3,4- b][1]oxa[4,6,10]triazacyclotridecin- 1(4H)-yl)-2-methylpropanenitrile::US20250313575, Ex-1.17

SMILES CC(C)(C#N)n1nc(C2CC2)c2c1OC[C@@H]1CC[C@H]1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778525   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778525(2-((10aR,12aR)-3-cyclopropyl-8- (trifluoromethyl)-...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent