BDBM778526 (10aR,12aR)-3-isopropyl-1-((R)- or (10aR,12aR)-3-isopropyl-1-((S)- tetrahydrofuran-3-yl)-8- (trifluoromethyl)- 1,4,10,10a,11,12,12a,13-octahydro- 5,9- (azeno)cyclobuta[k]pyrazolo[3,4- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-1.18

SMILES CC(C)c1nn(C2CCOC2)c2c1Nc1ncc(C(F)(F)F)c(n1)N[C@@H]1CC[C@H]1CO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778526   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778526((10aR,12aR)-3-isopropyl-1-((R)- or (10aR,12aR)-3-i...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent