BDBM778536 1'',3''-dimethyl-10''-(trifluoromethyl)- 1'',7'',8'',14''-tetrahydro-5''H- spiro[cyclopropane-1,6''- [9,13](azeno)pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine]::US20250313575, Ex-2.5

SMILES Cc1nn(C)c2c1OCC1(CC1)CNc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778536   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778536(1',3'-dimethyl-10'-(trifluoromethyl)- 1',7',8',14'...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent