BDBM778554 (10aR,12aS)- or (10aS,12aR)-3-cyclobutyl-1-methyl-8- (trifluoromethyl)-3,4,10,10a,11,12,12a,13- octahydro-5,9- (azeno)cyclobuta[k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-2.23

SMILES Cc1nn(C2CCC2)c2c1OC[C@H]1CC[C@H]1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778554   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778554((10aR,12aS)- or (10aS,12aR)-3-cyclobutyl-1-methyl-...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent