BDBM778563 (10aS,13aS)- or (10aR,13aR)-3-((1R,3S)-3- methoxycyclobutyl)-1-methyl-8- (trifluoromethyl)-3,4,10a,11,13a,14- hexahydro-10H,13H-5,9-(azeno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-2.32

SMILES COC1CC(n2nc(C)c3c2Nc2ncc(C(F)(F)F)c(n2)NC2COCC2CO3)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778563   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778563((10aS,13aS)- or (10aR,13aR)-3-((1R,3S)-3- methoxyc...)
Affinity DataIC50: 0.0910nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent