BDBM778578 ethyl (1R,2S)- or ethyl (1S,2R)-2-((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-3,4,10a,11,13a,14- hexahydro-10H,13H-5,9-(azeno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecin-1- yl)cyclopropane-1-carboxylate::US20250313575, Ex-2.47

SMILES CCOC(=O)[C@@H]1C[C@@H]1c1nn(C(C)C)c2c1OC[C@@H]1COC[C@H]1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778578   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778578(ethyl (1R,2S)- or ethyl (1S,2R)-2-((10aS,13aS)-3-i...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent