BDBM778579 2-((10aS,13aS)-3-cyclobutyl-8- (trifluoromethyl)-3,4,10a,11,13a,14- hexahydro-10H,13H-5,9-(azeno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecin-1-yl)-2- methylpropanenitrile::US20250313575, Ex-2.48

SMILES CC(C)(C#N)c1nn(C2CCC2)c2c1OC[C@@H]1COC[C@H]1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778579   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778579(2-((10aS,13aS)-3-cyclobutyl-8- (trifluoromethyl)-3...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent