BDBM778600 (10aS,13aS)-3-cyclobutyl-1-((1S,2S)- or (10aS,13aS)-3-cyclobutyl-1-((1R,2R)-2-(1- methyl-1H-pyrazol-4-yl)cyclopropyl)-8- (trifluoromethyl)-3,4,10a,11,13a,14- hexahydro-10H,13H-5,9-(azeno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-2.69

SMILES Cn1cc(C2CC2c2nn(C3CCC3)c3c2OC[C@@H]2COC[C@H]2Nc2nc(ncc2C(F)(F)F)N3)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778600   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778600((10aS,13aS)-3-cyclobutyl-1-((1S,2S)- or (10aS,13aS...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent