BDBM778603 (10aR,12aR)- or (10aS,12aS)-3-cyclobutyl-1-(oxetan-3-yl)- 8-(trifluoromethyl)- 3,4,10,10a,11,12,12a,13-octahydro-5,9- (azeno)cyclobuta[k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-2.72

SMILES FC(F)(F)c1cnc2nc1NC1CCC1COc1c(C3COC3)nn(C3CCC3)c1N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778603   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778603((10aR,12aR)- or (10aS,12aS)-3-cyclobutyl-1-(oxetan...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent