BDBM778627 (10aR,13aR)- or (10aS,13aS)-3-cyclobutyl-1-methyl-8- (trifluoromethyl)-3,4,10a,11,12,13,13a,14- octahydro-10H-5,9- (azeno)cyclopenta[k]pyrazolo[4,3- b][1]oxa[4,6, 10]triazacyclotridecine::US20250313575, Ex-5.5

SMILES Cc1nn(C2CCC2)c2c1OCC1CCCC1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778627   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778627((10aR,13aR)- or (10aS,13aS)-3-cyclobutyl-1-methyl-...)
Affinity DataIC50: 0.0870nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent