BDBM778633 ((10aR,12aR)-3-isopropyl-8- (trifluoromcthyl)-3,4,10,10a,11,12,12a,13- octahydro-5,9- (azeno)cyclobuta[k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecin-1- yl)methanol::US20250313575, Ex-6.5

SMILES CC(C)n1nc(CO)c2c1Nc1ncc(C(F)(F)F)c(n1)N[C@@H]1CC[C@H]1CO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778633   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778633(((10aR,12aR)-3-isopropyl-8- (trifluoromcthyl)-3,4,...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent