BDBM778635 ((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-3,4,10a,11,13a,14- hexahydro-10H,13H-5,9-(azeno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecin-1- yl)methanol::US20250313575, Ex-6.7

SMILES CC(C)n1nc(CO)c2c1Nc1ncc(C(F)(F)F)c(n1)N[C@@H]1COC[C@H]1CO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778635   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778635(((10aS,13aS)-3-isopropyl-8- (trifluoromethyl)-3,4,...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent