BDBM778636 (1R,2R)- or (1S,2S)-2-((10aS,13aS)-3- cyclopropyl-8-(trifluoromethyl)- 10a,11,13a,14-tetrahydro-10H,13H-5,9- (azeno)furo[3,4-k]pyrazolo[3,4- b][1]oxa[4,6,10]triazacyclotridecin-1(4H)- yl)cyclobutan-1-ol::US20250313575, Ex-6.8

SMILES O[C@H]1CC[C@@H]1n1nc(C2CC2)c2c1OC[C@@H]1COC[C@H]1Nc1nc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778636   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778636((1R,2R)- or (1S,2S)-2-((10aS,13aS)-3- cyclopropyl-...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent