BDBM778641 (R)-2-(3-isopropyl-11-methyl-8- (trifluoromethyl)-10,11,12,13-tetrahydro- 5,9-(azeno)pyrazolo[3,4- b][1]oxa[4,6,10]triazacyclotridecin-1(4H)- yl)-2-methylpropan-1-ol::US20250313575, Ex-7.4

SMILES CC(C)c1nn(C(C)(C)CO)c2c1Nc1ncc(C(F)(F)F)c(n1)N[C@H](C)CCO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778641   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778641((R)-2-(3-isopropyl-11-methyl-8- (trifluoromethyl)-...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent