BDBM778652 (10aR,12aR)-8-chloro-3-cyclobutyl- 1-methyl-3,4,10,10a,11,12,12a,13- octahydro-5,9- (metheno)cyclobuta[k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-13.3

SMILES Cc1nn(C2CCC2)c2c1OC[C@@H]1CC[C@H]1Nc1cc(ncc1Cl)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778652   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778652((10aR,12aR)-8-chloro-3-cyclobutyl- 1-methyl-3,4,10...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent