BDBM778654 (10aS,13aS)-3-isopropyl-1-methyl- 8-(trifluoromethyl)- 3,4,10a,11,13a,14-hexahydro- 10H,13H-5,9-(metheno)furo[3,4- k]pyrazolo[4,3- b][1]oxa[4,6,10]triazacyclotridecine::US20250313575, Ex-13.5

SMILES Cc1nn(C(C)C)c2c1OC[C@@H]1COC[C@H]1Nc1cc(ncc1C(F)(F)F)N2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 778654   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM778654((10aS,13aS)-3-isopropyl-1-methyl- 8-(trifluorometh...)
Affinity DataIC50: 0.0810nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details US Patent