BDBM77929 MLS002174170::SMR001261337::cid_25102468

SMILES CN(C)[C@H]1CC[C@@H](N2CCC3C[C@H]2c2cc(-c4cccc(C(F)(F)F)c4)ccc23)CC1

InChI Key InChIKey=GHYZYEWFTIVWLF-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77929   

TargetSigma intracellular receptor 2(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77929BDBM77929(US20250387403, Example Table1.27)
Affinity DataKi:  9.5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent