BDBM780142 4-[2-[([4-[3-(2-[imidazo[1,2- b]pyridazin-3-yl]ethynyl)-4- methylbenzamido]-2- (trifluoromethyl)phenyl]methyl) amino]ethyl]piperazine-1- carboxylate::US12440494, Compound 2

SMILES COC(=O)N1CCN(CCNCc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnc5cccnn45)c3)cc2C(F)(F)F)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780142   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Albert Einstein College of Medicine

US Patent
LigandPNGBDBM780142(4-[2-[([4-[3-(2-[imidazo[1,2- b]pyridazin-3-yl]eth...)
Affinity DataIC50: 17.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent