BDBM780144 3-(imidazo[1,2-b]pyridazin-3- ylethynyl)-4-methyl-N-(4-(((2-(4- oxopiperidin-1- yl)ethyl)amino)methyl)-3- (trifluoromethyl)phenyl)benzamide::US12440494, Compound 5

SMILES Cc1ccc(C(=O)Nc2ccc(CNCCN3CCC(=O)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780144   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Albert Einstein College of Medicine

US Patent
LigandPNGBDBM780144(3-(imidazo[1,2-b]pyridazin-3- ylethynyl)-4-methyl-...)
Affinity DataIC50: 30.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent