BDBM780145 3-(imidazo[1,2-b]pyridazin-3- ylethynyl)-4-methyl-N-(4-(((2-(4- (methylsulfonyl)piperazin-1- yl)ethyl)amino)methyl)-3- (trifluoromethyl)phenyl)benzamide::US12440494, Compound 6

SMILES Cc1ccc(C(=O)Nc2ccc(CNCCN3CCN(S(C)(=O)=O)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780145   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Albert Einstein College of Medicine

US Patent
LigandPNGBDBM780145(3-(imidazo[1,2-b]pyridazin-3- ylethynyl)-4-methyl-...)
Affinity DataIC50: 29.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details US Patent