BDBM781563 US12441707, Example 26

SMILES C[C@@H](Oc1ccc2[nH]nc(-c3cnc(N=S(C)(C)=O)c(F)c3)c2c1)c1c(Cl)cncc1Cl

InChI Key

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 781563   

TargetFibroblast growth factor receptor 3 [V555M](Human)
Tyra Biosciences

US Patent
LigandPNGBDBM781563(US12441707, Example 26)
Affinity DataKd:  1.80nMAssay Description:Test compounds were prepared as 111× stocks in 100% DMSO. Kds were determined using an 11-point 3-fold compound dilution series with three DMSO contr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM781563(US12441707, Example 26)
Affinity DataKd:  3.60nMAssay Description:Test compounds were prepared as 111× stocks in 100% DMSO. Kds were determined using an 11-point 3-fold compound dilution series with three DMSO contr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM781563(US12441707, Example 26)
Affinity DataKd:  14nMAssay Description:Test compounds were prepared as 111× stocks in 100% DMSO. Kds were determined using an 11-point 3-fold compound dilution series with three DMSO contr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 1(Human)
Tyra Biosciences

US Patent
LigandPNGBDBM781563(US12441707, Example 26)
Affinity DataKd:  17nMAssay Description:Test compounds were prepared as 111× stocks in 100% DMSO. Kds were determined using an 11-point 3-fold compound dilution series with three DMSO contr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent